Mobius® TFF 80 System

Processing large batch sizes in one run using single-use equipment is a challenge. The Mobius® TFF 80 system has been specifically developed for large-scale tangential flow filtration, with flow rate capabilities up to

80 L/min and up to 20 m2 of membrane area installed. The system maximizes the production yield and allows to achieve high concentration factors, minimizing unrecoverable volume. Its single-use flow path offers the flexibility to operate in functionally or fully closed mode.

Large-scale capabilities, with no compromise on quality

• 500 L and 200 L tanks, with up to 80 L/min diaphragm pump, and matching flow path design
• Holder for filter area up to 20 m² with Pellicon® cassettes and 18 m2 with single-use Pellicon® capsule manifolds

Designed for optimized yield and product recovery

• Tank geometry and mixing technology ensures product homogeneity, key for product quality during concentration and diafiltration
• Large tank volume to minimum working volume ratio for high concentration factor
• Highly drainable system with the lowest possible unrecoverable volume

Adapts to multi-product and multi-processing modes

• Single-use sensors and flow path eliminates cleaning requirements and risks for carryover from previous batches
• Closed mode of operation is possible with specifically designed flow path and consumables, allowing to reduce contamination risk while increasing flexibility and operator safety

Fully automated and user friendly

• Full automation with step edition CCP® Software
• Easy cassette installation via the central manifold and hydraulic compression on the holder
• Transparent clamshell design allows visual monitoring of process fluids within the flow path