MAS-100 Sirius® Microbial Air Sampler

General Specifications

• Portable stainless-steel (316L) air sampler designed for Grade A/B cleanrooms.
• Flow rates: 100 / 200 SLPM (1 m³ in 10 or 5 minutes).
• Compatible with 55 mm & 90 mm plates and Growth Direct cassettes.
• Battery-operated with magnetic lid and integrated HEPA H13 exhaust filter.
• Fully compliant with EN 17141, ISO 14698, and 21 CFR Part 11.
• Browser-based software — no installation required.

Distinctive Features

• Dual mass flow sensors for ±2.5% accuracy and drift detection.
• Automatic time synchronization (NTP) ensures timestamp accuracy within ±0.25%.
• VHP-decontaminable air path (validated to SAL 10⁻⁶).
• d₅₀ ≈ 1.1 µm @ 100/200 SLPM (below the 2 µm limit).
• Magnetic lid with tool-free plate adjustment.
• Wi-Fi & barcode data transfer with 21 CFR Part 11-compliant audit trail.
• One-button operation with automatic self-checks to prevent operator errors.

Large-scale Single-Use Virus Filtration system

• For volumes of 200 L to 2000+ L
• Magnus Viresolve® Pro holder can handle 0,51 m² to 3,06 m² of filter  and pre-filter HMI with data monitoring

• Constant Feed or Pressure regulation to optimize duration

Options

• 21CFR Part 11 recorder (with Modbus TCP/IP & Ethernet IP)
• Ultrasonic flowmeter (e.g. for IT testing, cumulative volume)
• Conductivity, pH
• Sterilizing filter on product recovery

Fully automated for continuous bind/elute in intensified and continuous processing (flow paths evaluated for continuous processing for up to 20 days prior to exchange)

• Working with 3 columns in parallel
• Flow rate: 1 to 120 L/h (16 mL/min to 2000 mL/min)
• Using our CCP® software
• Flexware available in open or closed processing
• In-line buffer dilution (up to 6 buffers)
• Reduced cost & prot A resin optimization (+ buffer consumption)
• Improved throughput & productivity
• High flexibility for intensification and continuous processes

Processing large batch sizes in one run using single-use equipment is a challenge. The Mobius® TFF 80 system has been specifically developed for large-scale tangential flow filtration, with flow rate capabilities up to

80 L/min and up to 20 m2 of membrane area installed. The system maximizes the production yield and allows to achieve high concentration factors, minimizing unrecoverable volume. Its single-use flow path offers the flexibility to operate in functionally or fully closed mode.

Large-scale capabilities, with no compromise on quality

• 500 L and 200 L tanks, with up to 80 L/min diaphragm pump, and matching flow path design
• Holder for filter area up to 20 m² with Pellicon® cassettes and 18 m2 with single-use Pellicon® capsule manifolds

Designed for optimized yield and product recovery

• Tank geometry and mixing technology ensures product homogeneity, key for product quality during concentration and diafiltration
• Large tank volume to minimum working volume ratio for high concentration factor
• Highly drainable system with the lowest possible unrecoverable volume

Adapts to multi-product and multi-processing modes

• Single-use sensors and flow path eliminates cleaning requirements and risks for carryover from previous batches
• Closed mode of operation is possible with specifically designed flow path and consumables, allowing to reduce contamination risk while increasing flexibility and operator safety

Fully automated and user friendly

• Full automation with step edition CCP® Software
• Easy cassette installation via the central manifold and hydraulic compression on the holder
• Transparent clamshell design allows visual monitoring of process fluids within the flow path

The BioContinuum Buffer Delivery Platform is a configurable offering of buffer concentrates, buffer dilution system, single-use assemblies, and services, tailored to provide the highest level of accuracy and precision for absolute certainty in buffer preparation and management. Whether designing a new, low-overhead facility or expanding capacity at an existing facility, the BioContinuum Buffer Delivery Platform delivers a competitive edge by reliably supplying process buffers from point of manufacturing to point of use, utilizing a fraction of the resources and facility space.

Key Benefits

• Simplify buffer preparation and management with an integrated offering of buffer concentrates, buffer delivery system, Mobius® MyWay single-use assemblies, and services
• Reduced manufacturing footprint devoted to buffer preparation and management
• Increase speed and flexibility in buffer preparation to meet the needs of evolving manufacturing demands
• Increase operator safety by reduced handling of dry powders
• Integrated quality using Emprove® raw materials, Mobius® MyWay single-use assemblies and robust volumetric dilution control

Mobius® Bioreactors are a scalable portfolio of stirred tank bioreactors that provide flexibility by configuring software, hardware, and single-use assemblies for use in suspension and adherent cell culture applications.

Our bioreactor platform has been designed to ensure that ease-of-use and operational flexibility at small scale can be translated to full scale production.

 Benefits

• Installation of single-use assemblies designed with you in mind for safe and repeatable operation
• 5:1 turndown ratio provides you with the most flexible seeding and growth strategy
• Works as a standalone system or integrated as part of your facility’s automation platform
• Demonstrated scalability of key engineering parameters gives you confidence to scale up your process.  
• Lynx® Connectors assure a critical sterile connection

Sterile, closed, disposable systems for sampling fluids from sterile and aseptic processes.

• Disposable and closed unit, ensuring process integrity, operator safety  and a representative sample

• Easy to use, handle and validate, improving operational efficiency
• Pre-sterilized, eliminating the need for cleaning and/or sterilization  between samples

• Accommodates a wide range of holders and sampling configurations for adaptable, flexible sampling options throughout your process